Diffusion functional-MRI (dfMRI) is thought to capture microstructural changes associated with neural activity. The water apparent diffusion coefficient decrease observed upon neuronal activity is hypothesized to be cell-swelling dependent. Yet, one of the confounding factors for dfMRI is that zero and nonzero b-values need to be acquired to deliver accurate changes in diffusivity and those images are typically separated by at least one repetition time. Incomplete initial Nutation Diffusion Imaging (INDI) was proposed as a method to acquire two images with different diffusion-weighting with separation of <50ms. Here, we performed INDI-fMRI experiments to report mean diffusivity changes using forepaw-stimulated rats.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords