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Abstract #0239

CVR-MRICloud: an automated online tool for the processing of cerebrovascular reactivity (CVR) MRI data

Zachary Baker1, Yang Li1, Peiying Liu1, Yue Li2, Michael I. Miller3, Susumu Mori1,4, and Hanzhang Lu1

1Department of Radiology, Johns Hopkins School of Medicine, Baltimore, MD, United States, 2AnatomyWorks LLC, Baltimore, MD, United States, 3Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States, 4Kennedy Krieger Institute, Baltimore, MD, United States

Cerebrovascular reactivity (CVR) has recently become a focus for many labs. However, CVR calculation has always required at least some degree of manual intervention. Therefore, our lab has developed CVR-MRICloud, a free, online, fully automated CVR processing pipeline. Our pipeline returns CVR maps, relative bolus arrival time maps, and region-of-interest CVR values. The maps are given in their original space as well as standardized MNI space. The pipeline has been shown to procure results corresponding to accepted CVR processing techniques that rely on manual intervention. This pipeline has potential to streamline other researchers’ acquisition of CVR values in subjects.

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