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Abstract #0238

Separation of Cardiac- and Respiratory-driven CSF Motions under Free Breathing based on Realtime Phase Contrast Imaging and S-Transform

Kagayaki Kuroda1,2,3, Tetsuya Tokushima3, Satoshi Yatsushiro1,4, Nao Kajiwara5, Tomohiko Horie5, Hideki Atsumi6, and Mitsumori Matsumae6

1Department of Human and Information Science, School of Into Science and Technology, Tokai University, Hiratsuka, Japan, 2Center for Frontier Medical Engieering, Chiba University, Chiba, Japan, 3Course of Electrical and Electronic Engineering, Graduate School of Engineering, Tokai University, Hiratsuka, Japan, 4BioSim Research Center, BioView Inc., Tokyo, Japan, 5Department of Radioligy, Tokai University Hospital, Isehara, Japan, 6Department of Neurosurgery, Tokai University School of Medicine, Isehara, Japan

To separately visualize respiratory- and cardiac-driven motions of intracranial cerebrospinal fluid (CSF) under free breathing, CSF velocity distribution in 6 healthy volunteers and 3 hydrocephalus patients were acquired with asynchronous real time phase contrast (PC). Spectrograms of CSF velocity waveform as well as ECG and respiratory signals were obtained by Stockwell Transform (ST), in which the length of a Gaussian window length was adaptively changed according to the time-varying frequency of the signals. Comparison with the conventional short-term Fourier transform (STFT) with fixed length window revealed that separation of respiratory and cardiac components of CSF motion was possible with ST.

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