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Abstract #0250

High-resolution MR imaging of human brain with multi-echo integrated SSFP

Huilou Liang1,2, Kaibao Sun1, Zhentao Zuo1,2,3, Jing An4, Yan Zhuo1,3, Danny J.J. Wang5, and Rong Xue1,2,6

1State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, 2University of Chinese Academy of Sciences, Beijing, China, 3CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Beijing, China, 4Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China, 5Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States, 6Beijing Institute for Brain Disorders, Beijing, China

Balanced SSFP (bSSFP) has been used in structural and functional MRI, but always suffered from banding artifacts. While phase cycling was widely used to reduce banding artifact, it would take more scan time. Recently, integrated SSFP (iSSFP) was introduced to acquire banding-free images in shorter scan time than phased-cycled bSSFP. In this work, multi-echo iSSFP was further developed to improve SNR and acquire ultrahigh-resolution images with moderate scan time at 7T. Phantom and in vivo experiments demonstrated that the combined image produced by weighted averaging of multi-echo iSSFP showed obvious SNR and contrast improvement and inherited the characteristics of bSSFP.

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