Abstract #0250

High-resolution MR imaging of human brain with multi-echo integrated SSFP

Huilou Liang^1,2, Kaibao Sun¹, Zhentao Zuo^1,2,3, Jing An⁴, Yan Zhuo^1,3, Danny J.J. Wang⁵, and Rong Xue^1,2,6

¹State Key Laboratory of Brain and Cognitive Science, Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, ²University of Chinese Academy of Sciences, Beijing, China, ³CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Beijing, China, ⁴Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China, ⁵Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, United States, ⁶Beijing Institute for Brain Disorders, Beijing, China

Balanced SSFP (bSSFP) has been used in structural and functional MRI, but always suffered from banding artifacts. While phase cycling was widely used to reduce banding artifact, it would take more scan time. Recently, integrated SSFP (iSSFP) was introduced to acquire banding-free images in shorter scan time than phased-cycled bSSFP. In this work, multi-echo iSSFP was further developed to improve SNR and acquire ultrahigh-resolution images with moderate scan time at 7T. Phantom and in vivo experiments demonstrated that the combined image produced by weighted averaging of multi-echo iSSFP showed obvious SNR and contrast improvement and inherited the characteristics of bSSFP.

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