Not only cerebral blood flow (CBF) but also cerebral blood volume (CBV)
plays an important role for the maintenance of cerebral blood perfusion. We
hypothesized that the ASL signal difference caused by vessel suppression (VS)
scheme should be dependent on arterial CBV fraction of total ASL signal. In
this study, we introduced modified two-compartments model based on ASL signal
with and without VS, so that we can calculate arterial volume fraction of total
ASL signal. The objective of this study is to demonstrate the feasibility of arterial
CBV map as well as CBF based on ASL imaging.