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Abstract #0396

Detection of fluid/solid tissue behavior of neurotumors by magnetic resonance elastography

Kaspar Josche Streitberger1, Ledia Lilaj1, Felix Schrank1, Jürgen Braun1, Josef Käs2, Karl Titus Hoffmann3, Martin Reiss-Zimmermann4, and Ingolf Sack5

1Charité - Universitätsmedizin Berlin, Berlin, Germany, 2University Leipzig, Leipzig, Germany, 3University Hospital Leipzig, Leipzig, Germany, 4Neuroradiology Center, Erfurt, Germany, 5Radiology, Charité-Universitätsmedizin Berlin, Berlin, Germany

It is known that glioblastoma (GB) display high heterogeneity and porosity (higher water content) than meningioma (MEN) suggesting a higher fluidity of GB than MEN. However, we will demonstrate by MR elastography (MRE) in patients and phantoms that the concept of fluidity cannot be naively transferred to brain tumors. Instead, the macroscopic viscosity-fluidity behavior of GB and MEN can be understood MRE of materials that comprise various amounts of water including materials with fibrillary architecture such as tofu. Similar to tofu, viscosity and fluidity in GB and MEN seem to reduce with increasing water content, indicating an ‘anomalous’ viscosity-fluidity behavior.

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