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Abstract #0401

Fast and Accurate Free-Breathing Whole-Heart 3D T2 Mapping

Aurelien Bustin1, Giorgia Milotta1, Radhouene Neji1,2, René Botnar1, and Claudia Prieto1

1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

T2 mapping is a promising quantitative imaging technique for the detection of myocardial edema. Conventionally, T2 mapping is performed using T2-prepared single-shot 2D acquisitions, acquiring multiple slices in several breath-holds. While showing high accuracy and reproducibility, breath-holding limits achievable spatial resolution and heart coverage and can be challenging in very sick patients. Here we propose a free-breathing whole-heart 3D T2 mapping technique with high isotropic spatial resolution in a clinically feasible scan time. This is achieved by combining an accelerated T2-prepared acquisition with patch-based reconstruction and dictionary-based signal matching. Feasibility of the proposed method was investigated in a standardized T1/T2 phantom and healthy subjects.

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