Meeting Banner
Abstract #0411

Advantages of tractography for the evaluation of intramuscular variances in human thigh muscles

Johannes Forsting1, Robert Rehmann1, Marlena Rohm1, Martijn Froeling2, and Lara Schlaffke1

1Neurology, BG-University Hospital Bergmannsheil, Bochum, Germany, 2Radiology, University Medical Center Utrecht, Utrecht, Netherlands

Muscle diffusion tensor imaging can indirectly provide information about muscular microstructure and architecture, which plays an increasing role in the evaluation of neuromuscular disease progression and treatment monitoring. The separation of different muscles is essential to evaluate intermuscular differences and variances. Here we have compared three methods to assess diffusion metrics of thigh muscles and showed, that tractography shows less variance in diffusion metrics than parameter maps. For the observed parameters FA, MD, RD and λ1 we found significant main effects of muscle, when using tractography, which was not found with manual annotation using ROI assessment of the parameter maps.

This abstract and the presentation materials are available to members only; a login is required.

Join Here