We introduce a method for imaging changes in healthy knee cartilage composition after joint loading with exercise that could be extended for use in subjects with joint disease. Six healthy participants were imaged before and at multiple time-points after a mild joint loading exercise. Our study demonstrates that quantitative MR mapping of T1ρ and T2 relaxation times of femorotibial cartilage is repeatable and able to demonstrate changes in cartilage composition in response to short-term joint loading exercise. Imaging cartilage compositional recovery after joint loading may present a new way of detecting early alterations in cartilage homeostasis associated with osteoarthritis.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords