Abstract #0419

Magic-Angle Effect on In Vivo T2 Mapping of Cartilage

Victor Casula^1,2, Olli Pekka Aro¹, Petri Paakkari³, Stefan Zbyn^4,5, Mika Nevalainen^1,6, Mikko J Nissi^1,7, and Miika T Nieminen^1,2,6

¹Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, ²Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland, ³Department of Applied Physics, University of Eastern Finland, Kuopio, Finland, ⁴Center for Magnetic Resonance Research, Minneapolis, MN, United States, ⁵Department of Radiology, University of Minnesota, Minneapolis, MN, United States, ⁶Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland, ⁷Department of Applied Physics, University of Eastern Finland, Oulu, Finland

Magic-angle effect in T2 relaxation time of knee cartilage was determined in vivo at clinical magnetic field strength. T2 was measured in healthy volunteer’s articular cartilage on a 3 T clinical scanner at two different orientations of the normal direction of the articular surface with respect to the main magnetic field. Magic-angle effect produced significant variations in the T2 values of healthy cartilage (up to 102% difference in deep cartilage), clearly demonstrating the importance of taking the orientation into account in clinical studies when interpreting cartilage degeneration using T2 mapping.

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