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Abstract #0452

MRI flow and volume quantification with internal validation and correlation to Fick and thermodilution catheterization derived values in pulmonary hypertension

Lindsey A Crowe1, Anne-Lise Hachulla1, Stéphane Noble2, Paola M Soccal3, Maurice Beghetti4, Frédéric Lador3, and Jean-Paul Vallée1

1Radiology, Geneva University Hospital, Medicine Faculty of the University of Geneva, Geneva, Switzerland, 2Cardiology, Geneva University Hospital, Geneva, Switzerland, 3Pulmonary Medicine, Geneva University Hospital, Geneva, Switzerland, 4Pediatric Cardiology, Geneva University Hospital, Geneva, Switzerland

Cardiac output (CO) determination is mandatory for the diagnosis work-up of pulmonary hypertension (PH). It is classically obtained by invasive methods such as indirect Fick (Qfick) and thermodilution (Qthermo) performed during right heart catheterisation (RHC). However, non-contrast, non-invasive and reliable methods may be preferred for clinical routine and post-treatment monitoring of patients. This study compared QFlow derived parameters (stroke volumes and cardiac index/ pulmonary and aortic flow) measured non-invasively in PH patients for internal validation of MRI and for comparison to RHC.

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