Meeting Banner
Abstract #0451

Enhanced non-invasive pressure drop and flow inefficiencies quantification via 4D-flow MRI

Joao Filipe Fernandes1, Alessandro Faraci1, Saul Myerson2, David Alexander Nordsletten1, and Pablo Lamata1

1School of Biomedical Engineering & Imaging Sciences, Kings College London, London, United Kingdom, 2Division of Cardiovascular Medicine, Radcliffe Department of Medicine, Oxford, United Kingdom

The pressure drop caused by convective effects is the standard clinic method for diagnosis of aortic stenosis using simplified Bernoulli. However simplified Bernoulli results in a reported overestimation that can be resolved with 4D-flow MRI and Simplified Advective Work-energy relative pressure (SAW). This work further refines SAW formulation and proposes an enhanced analysis of the positive and negative components of flow profile. Whereas forward SAW pressure drop correlates better with mean SB (R2=0.951) than full velocity profile by SAW (R2=0.901), backward SAW is totally independent of SB (R2=0.490), which makes the flow efficiency a potential predictive value for disease progression.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords