Abstract #0535

Characterization of BOLD hemodynamic response function in subcortical and cortical regions of human brain at 3T and 9.4T

Jung Hwan Kim¹, Amanda Taylor¹, Marc Himmelbach², Gisela Hagberg^2,3, Klaus Scheffler^2,3, and David Ress¹

¹Baylor College of Medicine, Houston, TX, United States, ²University of Tuebingen, Tuebingen, Germany, ³Max Planck Institute for Biological Cybernetics, Tubingen, Germany

Measurement of blood oxygen level dependent hemodynamic response function (BOLD HRF) can be used to evaluate neurovascular coupling and understand underlying physiology (e.g. oxygen uptake and blood flow). However, there is dearth of understanding subcortical neurovascular coupling, which is critical for brain health. Here, we characterize human subcortical HRFs at both 3T and 9.4T and compare them with HRFs in visual cortex.

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