Quantitative magnetization transfer (qMT) was used on swine kidneys with renal artery stenosis (RAS). The reproducibility of qMT at 1.5 and 3.0 T was tested in two RAS pigs and its utility in measuring renal fibrosis investigated in seven pigs at 3.0 T by comparing to histology. The Henkelman-Ramani equation was used to derive the bound pool fraction f. Comparable f values were obtained at 1.5 and 3.0 T. Measured f also correlated well with renal fibrosis by histology. In conclusion, qMT is reproducible at different field strengths and can be used to measure renal fibrosis in swine with RAS.
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