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Abstract #0582

Tomoelastography for the detection and characterization of liver tumors

Mehrgan Shahryari1, Georg Böning1, Uli Fehrenbach1, Jing Guo1, Heiko Tzschätzsch1, Jürgen Braun2, Timm Denecke1, and Ingolf Sack1

1Department of Radiology, Charité-Universitätsmedizin Berlin, Berlin, Germany, 2Institute of Medical Informatics, Charité-Universitätsmedizin Berlin, Berlin, Germany

Tomoelastography is a full field-of-view multifrequency MR elastography technique for high-resolution mapping of stiffness and viscosity of in-vivo tissues. We applied tomoelastography to patients with hepatic lesions and analyzed the accuracy of the method for tumor detection (contrast between lesion and liver tissue) and characterization (difference between malignant and benign tumors). Our results show that shear-wave-speed and phase angle of the complex shear modulus have good accuracy for detection (AUC=0.90 and 0.93, respectively) and characterization (AUC=0.92 and 0.88, respectively) of hepatic lesions. Tomoelastography can add important quantitative information about the biophysical constitution of liver tumors.

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