Tomoelastography is a full field-of-view multifrequency MR elastography technique for high-resolution mapping of stiffness and viscosity of in-vivo tissues. We applied tomoelastography to patients with hepatic lesions and analyzed the accuracy of the method for tumor detection (contrast between lesion and liver tissue) and characterization (difference between malignant and benign tumors). Our results show that shear-wave-speed and phase angle of the complex shear modulus have good accuracy for detection (AUC=0.90 and 0.93, respectively) and characterization (AUC=0.92 and 0.88, respectively) of hepatic lesions. Tomoelastography can add important quantitative information about the biophysical constitution of liver tumors.
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