Abstract #0583

Whole body 3.0 T MRI in Adult Lymphomas: Assessment of Quantitative Imaging Biomarkers for Nodal Disease Assessment

Arash Latifoltojar¹, Mark Duncan², Maria Klusmann³, Alan Bainbridge³, Deena Neriman³, Francesco Fraioli³, Jonathan Lambert³, Kirit Ardeshna³, and Shonit Punwani¹

¹Centre for Medical Imaging, University College London, Lodon, United Kingdom, ²University College London Hospital, London, United Kingdom, ³Univesriy College London Hospital, London, United Kingdom

Whole-body MRI (WB-MRI) is being increasingly advocated as an alternative/adjunct imaging platform in range of cancers including lymphomas. In this study we investigated the application of quantitative imaging biomarkers (QIBs) from a multi-parametric WB-MRI protocol for nodal disease assessment in adults’ lymphomas. We have shown that signal fat fraction (sFF) is more accurate for delineation of positive and/or negative disease compared to apparent diffusion coefficient (ADC) and might be a useful addition to widely used ADC quantitation.

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