Abstract #0586

High-frequency electrical conductivity imaging of rat brain tumor

Clementine Lesbats¹, Nitish Katoch², Atul Singh Minhas³, Hyung Joong Kim², Eung Je Woo², and Harish Poptani¹

¹Centre for Preclinical Imaging, University of Liverpool, Liverpool, United Kingdom, ²Department of Biomedical Engineering, Kyung Hee University, Seoul, Korea, Republic of, ³School of Engineering, Macquarie University, Sydney, Australia

Magnetic Resonance Electrical Property Tomography (MREPT) allowed the evaluation of the intra- and extracellular ionic changes in a rat model of brain tumor. A multi-echo T₂-weighted pulse sequence was used with 10 echos to map the B₁ field and reconstruct the tissue conductivity at 9.4T. Higher conductivity values were measured in the tumors compared to the healthy brain tissue, suggesting an increased ionic content and mobility in the tumor.

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