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Abstract #0591

Preoperative prediction of lymphovascular invasion in invasive breast cancer with DCE-MRI-based radiomics

Zhuangsheng Liu1, Bao Feng1,2, Yingjie Mei3, Qinxian Chen1, Changlin Li2, Yehang Chen2, Xiangmeng Chen1, Zhuoyong Li1, and Wansheng Long1

1radiology, Jiangmen Central Hospital, Jiangmen, China, 2Automation, Guilin University of Aerospace Technology, Guilin, China, 3Philips Healthcare, Guangzhou, China

Preoperative assessment of lymphovascular invasion (LVI) plays an important role in the therapeutic planning for individual breast cancer patient. A few MRI features have been shown to be associated with LVI, but remain controversial. This prospective study explored DCE-MRI-based radiomics for preoperative prediction of LVI in breast cancer. The results suggested that radiomics signature and MRI based axillary lymph node status were significantly correlated with LVI. The combined model, which incorporated the radiomics signature and MRI based axillary lymph node status, could preoperatively predict LVI with acceptable performance in the training and validation cohorts.

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