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Abstract #0616

Probing spatio-temporal information during attention modulations in humans with sub-second sampling of cortical depth dependent BOLD fMRI signals at 7T

Luca Vizioli1, Alexander Bratch1, Sudhir Ramanna1, Kamil Ugurbil1, and Essa Yacoub1

1CMRR, University of Minnesota, Minneapolis, MN, United States

Temporal dynamics of the BOLD signal have been recently exploited with fast TR fMRI. However, the ability to concurrently retain sub-millimeter spatial resolution along with high temporal resolution (e.g. =< ~600 ms TR), with sufficient SNR efficiency, has been elusive. Such a data set could provide unprecedented access to studying the human brain non-invasively. In this work, we push the spatio-temporal limits of 7T fMRI and investigate the possibility of exploiting BOLD temporal dynamics as a function of cortical depth, using spatio-temporal multi-voxel pattern analysis during attention modulations.

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