Meeting Banner
Abstract #0633

Building 4D neonatal cortical surface atlases using Wasserstein barycenter

Zengsi Chen1,2, Zhengwang Wu2, Liang Sun2, Fan Wang2, Li Wang2, Weili Lin2, John H Gilmore2, Dinggang Shen2, and Gang Li2

1China Jiliang University, Hangzhou, China, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, United States

Spatiotemporal (4D) neonatal cortical surface atlases are important tools for understanding the dynamic early brain development. To better preserve the sharpness and clarity of cortical folding patterns on surface atlases, we propose to compute the Wasserstein barycenter under the Wasserstein distance metric, for the construction of 4D neonatal surface atlases at each week from 39 to 44 postmenstrual weeks, based on a large-scale dataset with 764 neonates. Our atlases show sharper and more geometrically-faithful cortical folding patterns than the atlases built by the state-of-the-art method, thus leading to boosted accuracy for spatial normalization and facilitating early brain development studies.

This abstract and the presentation materials are available to members only; a login is required.

Join Here