This study aimed to compare the acquisition time, image quality, and diagnostic performance of three three-dimensional (3D) magnetic resonance cholangiopancreatography (MRCP) with compressed-sensing (CS) prototype protocols with those of conventional MRCP in a large cohort of patients with suspected pancreaticobiliary disorders, and to explore the effect of the in-plane phase-encoding direction on the image quality of small-field-of-view (FOV) breath-hold (BH) CS-MRCP (sFOV-BH-CS-MRCP). We found that CS-MRCP provides comparable image quality and diagnostic performance with significantly shortened scan time, and sFOV-BH-CS-MRCP should be acquired in the head-feet phase-encoding direction instead of the left-right direction.
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