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Abstract #0688

Ultra-High Resolution Whole-Brain DCE MRI makes Significant Difference in Estimating Permeability Maps for Cancer Patients

Joon Sik Park1, Eun Ji Lim1, Seung Hong Choi2, Chul-Ho Sohn2, and Jaeseok Park1

1Sungkyunkwan University, Korea, Korea, Republic of, 2Seoul National University Hospital, Seoul, Korea, Republic of

An ultra-high resolution, whole-brain DCE MRI with a temporal resolution of 1.5sec (3~4 times higher than conventional routine) and a spatial resolution of isotropic 1.0mm3 (5~6 times higher than conventional routine) is introduced in a real clinical setting to address problems related to arterial input function and partial volumes for precise estimation of vascular permeability information in brain cancer patients. Compared with conventional routine vendor-provided method, the proposed ultra-high resolution DCE MRI produces significant differences in permeability maps particularly for both Ktrans and ve.

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