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Abstract #0691

Brain-component mapping with Inversion-Recovery bSSFP

Julian Pfister1,2,3, Martin Blaimer1, Walter H Kullmann3, Andreas J Bartsch4, Peter M Jakob2, and Felix A Breuer1

1Magnetic Resonance and X-ray Imaging, Fraunhofer Development Center X-ray Technology (EZRT), Würzburg, Germany, 2Experimental Physics 5, University of Würzburg, Würzburg, Germany, 3Institute of Medical Engineering, University of Applied Sciences Würzburg-Schweinfurt, Schweinfurt, Germany, 4Neuroradiology, University of Heidelberg, Heidelberg, Germany

An inversion recovery (IR) bSSFP measurement allows to calculate quantitative parameter maps assuming mono-exponential signals. However, the measured signals often show multi-exponential behavior due to partial volume effects or tissue microstructure. With IR bSSFP it is possible to extract a spectrum of the apparent relaxation times T1* and hence to identify multiple components in each voxel. By integration over specific T1* ranges, different brain-components like white matter, gray matter or CSF can be mapped. In this work, we demonstrate that even short-living components such as myelin water are detected providing helpful information for diagnostic purposes, e.g. in neurodegenerative diseases.

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