Abstract #0709

Utility of simultaneous T1 and T2 mapping with MR Fingerprinting (MRF) for bowel wall imaging in Crohn’s Disease

Verena Carola Obmann^1,2, Nicole Seyfried³, Wei-Ching Lo⁴, Ananya Panda⁵, Yun Jiang¹, Katherine Wright¹, Preetika Sinh⁶, Jeffrey Katz⁶, Maneesh Dave⁶, Pingfu Fu⁷, Kathleen Ropella-Panagis¹, and Vikas Gulani¹

¹Radiology, Case Western Reserve University, Cleveland, OH, United States, ²Diagnostic, Interventional and Pediatric Radiology, Inselspital, Bern, Switzerland, ³School of Medicine, Case Western Reserve University, Cleveland, OH, United States, ⁴Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ⁵Radiology, Mayo Clinic, Rochester, MN, United States, ⁶Gastroenterology and Digestive Health, University Hospitals Cleveland Medical Center, Cleveland, OH, United States, ⁷Biostatistics, Case Western Reserve University, Cleveland, OH, United States

The feasibility of using MRF to assess T1 and T2 relaxation times in the intestine for the evaluation of inflammatory bowel disease was explored. 52 patients with Crohn’s Disease underwent MR enterography with MRF acquisitions through the bowel. T1 relaxation times allowed quantitative differentiation between unaffected segments and inflamed segments, p = 0.004. T2 relaxation times further allowed distinction between segments with active and chronic fibrotic changes, p = 0.003.

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