Meeting Banner
Abstract #0710

MRI assessed dysmotility and texture analysis in the terminal ileum and small bowel: A pilot study comparison between Irritable Bowel Syndrome (IBS) patients with bloating and healthy controls

Ruaridh Gollifer1, Alex Menys1, Natalia Zarate-Lopez2, Dave Chatoor2, Anton Emmanuel2, Stuart Taylor1, and David Atkinson1

1CMI, UCL, London, United Kingdom, 2Department of Gastroenterology, University College London Hospitals, London, United Kingdom

Gastrointestinal symptoms in irritable bowel syndrome (IBS) occur without any obvious structural gut abnormality. This pilot study is based on abnormal ileo-caecal motility function suggested by wireless capsule data, with potential reflux of caecal contents back into the terminal ileum (TI). We compared constipation-predominant IBS (IBS-C) patients with bloating to healthy controls, through texture analysis and motility measures. We found TI temporal variation of motility was significantly higher in healthy controls. There was also a difference in the TI to small bowel texture analysis contrast ratio, but this was only significant in BTFE sequences.

This abstract and the presentation materials are available to members only; a login is required.

Join Here