Gastrointestinal symptoms in irritable bowel syndrome (IBS) occur without any obvious structural gut abnormality. This pilot study is based on abnormal ileo-caecal motility function suggested by wireless capsule data, with potential reflux of caecal contents back into the terminal ileum (TI). We compared constipation-predominant IBS (IBS-C) patients with bloating to healthy controls, through texture analysis and motility measures. We found TI temporal variation of motility was significantly higher in healthy controls. There was also a difference in the TI to small bowel texture analysis contrast ratio, but this was only significant in BTFE sequences.