Meeting Banner
Abstract #0740

Intracranial vessel wall thickness measurements: A post-mortem comparison between hypertensive patients and controls

K. M. van Hespen1, H. J. Kuijf2, P. R. Luijten3, J. Hendrikse3, and J. J.M. Zwanenburg3

1Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands, 2Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands, 3Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands

For the intracranial arteries, only a few studies have investigated arterial wall thickening. In this post-mortem, explorative study we investigated the effect of hypertension on vascular remodeling in the Circle of Willis in male and female groups using 7T MRI. Circle of Willis specimens were scanned at ultra-high resolution(0.11mm isotropic). Vessel wall thickness and vessel wall area were measured at 21 locations across the major arterial branches. Results showed a larger vessel wall thickness and area in the female hypertension subgroup in four different arteries as compared to the control group(p<0.05). Male hypertension and control groups showed no significant difference.

This abstract and the presentation materials are available to members only; a login is required.

Join Here