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Abstract #0767

High-Resolution Diffusion MRI: In-Vivo Demonstration of the SNR Benefit of Single-Shot Spiral Acquisition vs. EPI

Yoojin Lee1,2, Bertram J Wilm1, Zoltan Nagy2, and Klaas P Prüssmann1

1Institute for Biomedical Engineering, ETH Zürich, Zürich, Switzerland, 2Laboratory for Social and Neural Systems Research, University of Zürich, Zürich, Switzerland

Spiral acquisition for diffusion-weighted imaging (DWI) has become possible with recent development of dynamic field monitoring and image reconstruction. In this work, we demonstrate high-quality in-vivo spiral DWI at high in-plane resolution (1mm) with minimal artifacts. In addition, we confirm the expected signal-to-noise ratio (SNR) gain of spiral- compared to echo-planar-imaging (EPI) readouts both theoretically and experimentally at varied resolutions and acceleration factors. An SNR gain up to 91% was measured in white matter. In conclusion, spiral acquisition provides improved SNR especially at high image resolutions.

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