Abstract #0772

Toward high-SNR, motion-robust diffusion MRI of the liver using optimized gradient waveforms, non-gated free-breathing acquisitions, and motion-corrected averaging

Ruiqi Geng^1,2, Yuxin Zhang^1,2, Huiwen Luo^3,4, and Diego Hernando^1,2

¹Radiology, University of Wisconsin, Madison, Madison, WI, United States, ²Medical Physics, University of Wisconsin, Madison, Madison, WI, United States, ³Biomedical Engineering, Vanderbilt University, Nashville, TN, United States, ⁴Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States

Liver DWI suffers from signal voids introduced by elastic motion, mis-registration due to respiratory motion and low SNR. We propose to develop and evaluate a novel free-breathing DWI technique appropriate for the abdomen, in order to provide high SNR efficiency with predictable scan times, while avoiding motion-related artifacts. Evaluations showed that compared to respiratory-triggering acquisitions, the proposed DWI technique provided higher SNR and predictable scan times. Further, a motion-corrected averaging algorithm has the potential to correct for motion-related artifacts. Using optimized gradient waveforms, non-gated free-breathing acquisitions, and motion-corrected averaging techniques, high-SNR and motion-robust DWI of the liver may be achieved.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.