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Abstract #0773

An efficient reconstruction by combining tilted-CAIPI with eddy-current calibration for high-resolution distortion-free diffusion imaging using DIADEM

Myung-Ho In1, Zijing Dong2,3, Kawin Setsompop2,4, Daehun Kang1, Uten Yarach1, Yunhong Shu1, Joshua D Trzasko1, John Huston1, and Matt A Bernstein1

1Department of Radiology, Mayo Clinic, Rochester, MN, United States, 2A. A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States, 3Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, 4Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States

As a variant of multi-shot echo-planar imaging, DIADEM (Distortion-free Imaging: A Double Encoding Method) enables high-resolution distortion-free imaging, but the prolonged scan time can be a major challenge. Recently, a novel parallel imaging approach, termed tilted-CAIPI, was suggested to unfold highly accelerated DIADEM data and to substantially reduce the acquisition time. However, the reconstructed image still suffers from eddy-current-induced geometric distortions in diffusion-weighted data. In this work, it is demonstrated that the DIADEM reconstruction becomes more efficient and practical after combining the tilted-CAIPI with the eddy-current calibration approaches.

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