As a variant of multi-shot echo-planar imaging, DIADEM (Distortion-free Imaging: A Double Encoding Method) enables high-resolution distortion-free imaging, but the prolonged scan time can be a major challenge. Recently, a novel parallel imaging approach, termed tilted-CAIPI, was suggested to unfold highly accelerated DIADEM data and to substantially reduce the acquisition time. However, the reconstructed image still suffers from eddy-current-induced geometric distortions in diffusion-weighted data. In this work, it is demonstrated that the DIADEM reconstruction becomes more efficient and practical after combining the tilted-CAIPI with the eddy-current calibration approaches.
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