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Abstract #0774

High-Resolution Isotropic Diffusion MRI Using Simultaneous Multi-slab (SMSlab) Acquisition

Erpeng Dai1,2, Yuhsuan Wu1, and Hua Guo1

1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Radiology, Stanford University, Stanford, CA, United States

3D multi-slab acquisition is an important technique for high-resolution isotropic diffusion MRI. To further accelerate the acquisition, simultaneous multi-slice (SMS) excitation can be combined with multi-slab, termed simultaneous multi-slab (SMSlab). Previously it has been demonstrated that the SMSlab un-folding problem can be solved using a 3D Fourier encoding framework. When applying SMSlab to diffusion MRI, the main challenge is how to simultaneously un-fold the excited multiple slices/slabs and correct the inter-shot phase variations. To achieve this, a delicate navigator acquisition is designed and a POCS-enhanced k-space phase correction method is used in this study.

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