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Abstract #0799

Magnetic resonance shear wave elastography in cadaver breast

Allison Payne1, Lorne Hofstetter1, Riley Haag-Roeger2, Henrik Odeen1, and Dennis Parker1

1Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, 2Bioengineering, University of Utah, Salt Lake City, UT, United States

Tissue stiffness is a known marker of malignancy and has been shown to change due to thermal therapies. A shear wave elastography technique compatible with magnetic resonance guided focused ultrasound technology is demonstrated in a cadaver breast specimen. Volumetric shear wave speed maps acquired using a multiple-point sonication pattern before and after an MRgFUS ablation demonstrate that a change in shear wave speed can be detected. This technique provides a functional stiffness metric that is complementary to currently used monitoring and assessment techniques in MRgFUS treatments.

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