Abstract #0898

Brain Tumor Simulator: Creating Ground Truth for Evaluation of Complex MR Acquisition and Reconstruction Methodologies

Junzhou Chen¹, Leah Henze Bancroft², Jorge Jimenez³, Anja van der Kolk², Aaron S. Field², Azam S. Ahmed⁴, Roberta M. Strigel², and Walter F. Block¹

¹Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ²Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, ³Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁴Department of Neurological Surgery, University of Wisconsin-Madison, Madison, WI, United States

New dynamic MRI methods promise to better characterize and monitor the vexing problem of brain cancer. Assessing these methods and the assumptions they rely upon is difficult as 1) no known gold standard is available for brain tumors and 2) the time window of availability for brain cancer volunteers is narrow. We present a simulator that generates realistic, heterogeneous, tumor models overlaid over normal brain tissue with user-specified permeability parameters. The simulator generates raw data for arbitrary k-space acquisition strategies. Using this simulator, new methodologies for various tumor types and sizes can be assessed before the first volunteer is ever recruited.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.