Previous studies have shown good correlation between ASL and DSC vascular parameters as predictors of glioma grade, indication an option to omit DSC imaging in light of the recent finding of gadolinium deposition in the brain. However, in general these comparative studies were conducted before the recent update of the World Health Organisation classification of brain tumours. This study shows the potential of voxelwise correlations of vascular parameters obtained with ASL and DSC as predictors of IDH-mutation status in non-enhancing glioma and highlights that IDH-mutation status should be included in comparative studies of ASL and DSC vascular parameters in glioma.
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