Abstract #0903

A Brain Morphometric MRI Study on Patients with Suprasellar Tumors: Preoperative and Postoperative Assessment

Qingping Chen^1,2, Jianyou Ying³, Zhentao Zuo^1,2,4, Rui Wang³, Taoyang Yuan³, Lu Jin³, Chuzhong Li³, Songbai Gui³, Peng Zhao⁴, Chunhui Liu⁵, and Yazhuo Zhang^3,5,6,7

¹State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, ²Sino-Danish College, University of Chinese Academy of Sciences, Beijing, China, ³Beijing Neurosurgical Institute, Capital Medical University, Beijing, China, ⁴The Innovation Center of Excellence on Brain Science, Chinese Academy of Sciences, Beijing, China, ⁵Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China, ⁶Beijing Institute for Brain Disorders Brain Tumor Center, Beijing, China, ⁷China National Clinical Research Center for Neurological Diseases, Beijing, China

It has been reported that suprasellar tumors affect patients’ visual field and visual functional network. In this study, longitudinal brain morphometric assessment was performed pre- and post-operation based on 13 suprasellar tumors patients. The gray matter volume of rectus increases, but insular, caudate, and putamen decrease after operation. In addition, the gray matter volume can be predicted by tumor chiasmal lift length. What’s more, at the high-level visual cortex, the surface thickness becomes thicker after operation. We believe this study can improve the preoperative and postoperative assessment of suprasellar tumors in the future.

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