Abstract #0955

Density-Weighted Concentric Ring Trajectory using simultaneous multi-slice (SMS) acceleration: 3D Metabolite-cycled Magnetic Resonance Spectroscopy Imaging at 3 T

Pingyu Xia¹, Xin Shen², Xiaopeng Zhou¹, Mark Chiew³, Albert Thomas⁴, Ulrike Dydak^1,5, and Uzay Emir^1,2

¹School of Health Sciences, Purdue University, West Lafayette, IN, United States, ²Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States, ³Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, United Kingdom, ⁴Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, ⁵Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States

In this study, we proposed a novel simultaneous multi-slice (SMS) density weighted (DW) concentric ring trajectory (CRT) metabolite-cycling Magnetic Resonance Spectroscopy Imaging (MRSI) sequence to alleviate some conventional MRSI drawbacks, e.g. long acquisition time, eddy current artifacts, and side lobe artifacts. The sequence was tested on 5 healthy subjects, showing the feasibility of acquiring three slices of high-quality water-only and metabolite spectra simultaneously with a resolution of 5mm X 5mm X 10mm within 20 minutes.

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