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Abstract #0955

Density-Weighted Concentric Ring Trajectory using simultaneous multi-slice (SMS) acceleration: 3D Metabolite-cycled Magnetic Resonance Spectroscopy Imaging at 3 T

Pingyu Xia1, Xin Shen2, Xiaopeng Zhou1, Mark Chiew3, Albert Thomas4, Ulrike Dydak1,5, and Uzay Emir1,2

1School of Health Sciences, Purdue University, West Lafayette, IN, United States, 2Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States, 3Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, United Kingdom, 4Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, 5Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States

In this study, we proposed a novel simultaneous multi-slice (SMS) density weighted (DW) concentric ring trajectory (CRT) metabolite-cycling Magnetic Resonance Spectroscopy Imaging (MRSI) sequence to alleviate some conventional MRSI drawbacks, e.g. long acquisition time, eddy current artifacts, and side lobe artifacts. The sequence was tested on 5 healthy subjects, showing the feasibility of acquiring three slices of high-quality water-only and metabolite spectra simultaneously with a resolution of 5mm X 5mm X 10mm within 20 minutes.

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