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Abstract #0978

Highly Accelerated 3D Whole-Heart Isotropic Sub-Millimeter CMRA with Non-Rigid Motion Correction

Aurelien Bustin1, Teresa Correia1, Imran Rashid1, Gastao Cruz1, Radhouene Neji1,2, René Botnar1, and Claudia Prieto1

1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

Whole-heart sub-millimeter isotropic coronary magnetic resonance angiography (CMRA) provides detailed information of the coronary arteries and surrounding vessels. Recently, a patch-based reconstruction technique (3D PROST) has been proposed to achieve sub-millimeter isotropic resolution CMRA in a predictable scan time. However, this approach only corrects for 2D translational respiratory motion of the heart and image quality can be affected by residual non-rigid motion. Here we propose to integrate 3D PROST into a highly accelerated non-rigid motion correction framework to achieve high quality whole-heart free-breathing isotropic sub-millimeter Cartesian CMRA in a clinically feasible scan time. The feasibility of the proposed method was tested in seven healthy subjects and two patients with suspected coronary artery disease.

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