Abstract #0994

Simultaneous T1, T2 and ADC Mapping in Prostate Cancer and BPH using STimulated-Echo based Mapping (STEM)

Yuxin Zhang^1,2, Shane A Wells², Alejandro Roldán-Alzate^2,3,4, and Diego Hernando^1,2

¹Medical Physics, University of Wisconsin Madison, Madison, WI, United States, ²Radiology, University of Wisconsin Madison, Madison, WI, United States, ³Mechanical Engineering, University of Wisconsin Madison, Madison, WI, United States, ⁴Biomedical Engineering, University of Wisconsin Madison, Madison, WI, United States

A method for simultaneous T1, T2 and Apparent Diffusion Coefficient (ADC) mapping, STimulated-Echo based Mapping (STEM), has been proposed to achieve rapid and co-registered multi-slice T1, T2 and ADC maps within a moderate scan time. In this study, the STEM method is optimized for prostate imaging and evaluated in 16 patients with suspected prostate cancer (PCa) or benign prostatic hyperplasia (BPH). T1, T2 and ADC maps were successfully estimated and compared among BPH, PCa and healthy prostate tissues.

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