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Abstract #0996

In-vivo diffusion imaging of hippocampal network with 600 μm isotropic resolution at 7T

Farshid Sepehrband1, Ryan P Cabeen1, Jin Jin1,2,3, Justin P Haldar4, and Arthur W Toga1

1Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States, 2School of Information Technology and Electrical Engineering, University of Queensland, Brisbane, Australia, 3Siemens Medical Solutions USA, Inc., Los Angeles, CA, United States, 4Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, CA, United States

Neuroimaging findings indicate that neurological disorders differentially target distinct subregions of the hippocampal circuit 1. Therefore, the ability to image hippocampal network is essential to study the mechanism of the disease pathophysiology. Here we propose a novel framework that enables high-resolution intra-hippocampal macro-structural and network diffusion imaging.

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