Abstract #0996

In-vivo diffusion imaging of hippocampal network with 600 μm isotropic resolution at 7T

Farshid Sepehrband¹, Ryan P Cabeen¹, Jin Jin^1,2,3, Justin P Haldar⁴, and Arthur W Toga¹

¹Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States, ²School of Information Technology and Electrical Engineering, University of Queensland, Brisbane, Australia, ³Siemens Medical Solutions USA, Inc., Los Angeles, CA, United States, ⁴Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, CA, United States

Neuroimaging findings indicate that neurological disorders differentially target distinct subregions of the hippocampal circuit ¹. Therefore, the ability to image hippocampal network is essential to study the mechanism of the disease pathophysiology. Here we propose a novel framework that enables high-resolution intra-hippocampal macro-structural and network diffusion imaging.

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