Free-Breathing Liver Fat Quantification in Adults with NAFLD using a 3D Stack-Of-Radial MRI Technique

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide and can lead to liver failure. Conventional Cartesian MRI techniques can quantify liver fat. However, Cartesian MRI requires breath-holding to avoid respiratory motion artifacts in the liver, which may be challenging for many patients. Therefore, we evaluated the accuracy and repeatability of a recently developed free-breathing 3D stack-of-radial liver fat quantification technique in adults with NAFLD at 3 T. The new free-breathing technique demonstrated good repeatability and accuracy compared to conventional breath-holding Cartesian MRI and breath-holding MR spectroscopy.