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Abstract #1029

3D Arterial Spin Labeling Imaging of Arterial and Portal-Venous Perfusion in Human Liver at 3 Tesla under Free Breathing: Preliminary Results

Petros Martirosian1, Bernd Kühn2, Jakob Weiss3, Ulrich Grosse3, Rüdiger Hoffmann3, Martin Schwartz1,4, Berthold Kiefer2, Konstantin Nikolaou3, and Fritz Schick1

1Section on Experimental Radiology, University Hospital of Tübingen, Tübingen, Germany, 2Siemens Healthcare GmbH, Erlangen, Germany, 3Department of Diagnostic and Interventional Radiology, University Hospital of Tübingen, Tübingen, Germany, 4Institute of Signal Processing and System Theory, University of Stuttgart, Stuttgart, Germany

Measurement of hepatic arterial perfusion is important for assessment of chronic liver diseases and characterization of liver lesions. The aim of this study was to investigate the capability of a 3D-PCASL sequence for measurement of arterial, portal-venous and global perfusion of the liver under free respiration. It is demonstrated that the presented method provides high quality ASL perfusion images of the liver under free breathing conditions. Results in a patient with hepatocellular carcinoma clearly indicate high and quantitatively measurable arterial perfusion of lesions, although direct measurement of the clearly lower ASL signal of arterial perfusion in normal liver tissue is usually limited by background noise.

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