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Abstract #1045

Stirred CSF Measured by Low b-value DTI

Yoshitaka Bito1, Kuniaki Harada1, Hisaaki Ochi2, and Kohsuke Kudo3

1Healthcare Business Unit, Hitachi, Ltd., Tokyo, Japan, 2Research and Development Group, Hitachi, Ltd., Tokyo, Japan, 3Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan

Cerebrospinal fluid (CSF) plays an important role in clearance systems of the brain. There have been many studies on bulk flow of CSF; however, there have been few studies on complex flow like pseudo-random movement of CSF. In this paper, we investigate locally “stirred” CSF by using low b-value diffusion tensor imaging (DTI). Measured DTI shows inhomogeneous physiology of CSF, including extremely high and anisotropic diffusion tensors around the middle-cerebral artery. It demonstrates that the low b-value DTI will be useful in estimating local drainage of CSF.

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