T2 weighting intracranial vessel wall MR imaging provides good contrast to discriminate various important plaque components and is a good tool to differentiate intracranial vasculopathy. However, the strong CSF signal in T2-weighted images interfere the depiction of the vessel wall. In this study, we proposed to use T2IR preparation module combined with T2-weighted SPACE for whole brain intracranial vessel wall imaging, the T2IR pulses were used to suppress CSF while minimizing its effect on the signal reduction from T2w SPACE. This new technique was first evaluated in healthy volunteers and then tested on some stroke patients.
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