Abstract #1122

Towards QSM Challenge 2.0: Creation and Evaluation of a Realistic Magnetic Susceptibility Phantom

José P. Marques¹, Berkin Bilgic^2,3,4, Jakob Meineke⁵, Carlos Milovic^6,7, Kwok-shing Chan¹, Wietske van der Zwaag⁸, Renaud Hedouin¹, Christian Langkammer⁹, and Ferdinand Schweser^10,11

¹Donders Institute for Brain Cognition and Behaviour, Radboud University, Nijmegen, Netherlands, ²Athinoula A. Martinos Centre for Biomedical Imaging, Charlestown, MA, United States, ³Department of Radiology, Harvard Medical School, Boston, MA, United States, ⁴Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, ⁵Philips Research, Hamburg, Germany, ⁶Department of Electrical Engineering, Pontificia Universidad Catolica de Chile, Santiago, Chile, ⁷Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile, ⁸Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, ⁹Department of Neurology, Medical University of Graz, Graz, Austria, ¹⁰Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, United States, ¹¹Center for Biomedical Imaging, Clinical and Translational Science Institute, University at Buffalo, The State University of New York, Buffalo, NY, United States

We present the creation of a modular and realistic digital phantom to serve as a ground-truth to assess the quality of different reconstruction algorithms for Quantitative Susceptibility Mapping (QSM). The phantom is derived from high-resolution, quantitative MRI data of a healthy volunteer, features a realistic morphology including a non piece-wise constant susceptibility distribution. Varying degrees of complexity can be realized, for example by adding the effects of tissue microstructure, down sampling or adding background-fields. The freely available phantom will be used in the upcoming QSM Reconstruction challenge.

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