Meeting Banner
Abstract #1165

Accelerated spin-echo fMRI using Multisection Excitation by Simultaneous Spin-echo Interleaving (MESSI) with ‘complex-basis’ RF-encoded generalized SLIce Dithered Enhanced Resolution Simultaneous Multi-Slice (MESSI-gSlider-SMS)

SoHyun Han1,2, Congyu Liao1,2, Mary Kate Manhard1,2, Jonathan R. Polimeni1,2,3, and Kawin Setsompop1,2,3

1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Department of Radiology, Harvard Medical School, Boston, MA, United States, 3Harvard-MIT Division of Health Science and Technology, Cambridge, MA, United States

High spatiotemporal resolution spin-echo fMRI is challenging as it requires a long echo time to generate BOLD-contrast, resulting in longer repetition times. We propose a new technique, Multisection Excitation by Simultaneous Spin-echo Interleaving (MESSI), which utilizes the dead time in long TE acquisitions to improve the slice-coverage of SE-fMRI. For further accelerations, we combine the MESSI with both ‘complex-basis’ RF-encoded gSlider and conventional-SMS. Compared with standard SE-EPI acquisition with the same TR, the proposed MESSI-gSlider acquisition shows comparable tSNR but with eight-fold increase in slice-coverage. This method should be beneficial for applications requiring high spatiotemporal resolution SE-fMRI with whole-brain coverage.

This abstract and the presentation materials are available to members only; a login is required.

Join Here