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Abstract #1173

Resting-state fMRI at UHF: Optimizing BOLD sensitivity by using plug-and-play parallel transmission at 7T

Vincent Gras1, Benedikt A. Poser2, Xiaoping Wu3, Raphaël Tomi-Tricot1, and Nicolas Boulant1

1Neurospin, CEA, Gif-sur-Yvette, France, 2Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, 3Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

The 7T Human Connectome Project (HCP) resting-state fMRI (RS-fMRI) protocol employs slice-accelerated multiband (MB) EPI with a total of 10-fold acceleration (MB 5 and in-plane 2). Such highly accelerated acquisitions provide exquisite temporal resolution at good sensitivity in most cortical regions, but quickly become very SNR starved in transmit field (B1+) deprived regions. This can be mitigated using parallel RF transmission (pTX), which however usually comes at the expense of time-consuming calibrations and pulse computations. This work shows experimentally with HCP-style RS-fMRI scans that a plug-and-play alternative for B1+ mitigation using pTX is possible with multiband Universal Pulses.

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