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Abstract #1200

Intravoxel-Incoherent-Motion Diffusion Weighted MR Imaging for Early Assessment of Graft Function in Kidney Transplant

Yi-Hsin Tsai1, Yung-Chieh Chang2,3, Mu-Chih Chung4, Hao-Chung Ho5, Clayton Chi-Chang Chen1,2, and Jyh-Wen Chai2

1Department of Education, Taichung Veterans General Hospital, Taichung, Taiwan, 2Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan, 33Department of Electrical Engineering, National Chung Hsing University, Taichung, Taiwan, 4Division of Nephrology, Taichung Veterans General Hospital, Taichung, Taiwan, 5Division of Urology, Taichung Veterans General Hospital, Taichung, Taiwan

There are currently many different criteria for defining delayed graft function in patients with renal transplant, some of which require subjective decision-making, others require observation over time. We propose the intravoxel incoherent motion MR sequence as a method to acquire objective, sensitive biomarkers early after transplantation. The proposed method is shown to provide information of rapid-moving fluid in addition to conventional slow diffusion from the renal parenchema, and have the potential to assess the renal graft condition from both diffusion-based and perfusion-based view.

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