Abstract #1209

Multi-Vendor Validation of Controlled Saturation Magnetization Transfer (CSMT) for VFA T1 and T2 mapping

Rui Pedro A G Teixeira^1,2, Radhouene Neji^2,3, Tobias Wood⁴, Ana A. Baburamani¹, Shaihan J Malik², and Jo V Hajnal^1,2

¹Centre for the Developing Brain,School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ²Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ³MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, ⁴Neuroimaging, King's College London, London, United Kingdom

White matter T₁values have been reported to range from 699ms-1735ms¹. The recently introduced Controlled Saturation Magnetization Transfer (CSMT)² qMRI approach suggests this might be due to MT effects. In this work employ the CSMT framework on 3 major MR manufacturers and demonstrate it allows a decrease in variability of T₁/T₂ estimation both in phantom and in-vivo.

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