Abstract #1229

Initial Clinical Evaluation of Quantitative Ultra-high Resolution First-pass Spiral Perfusion Imaging with Whole Heart Coverage in Patients with Ischemic Heart Disease at 3T

Yang Yang¹, Austin Robinson¹, Roshin Mathew¹, Christopher M Kramer^1,2, and Michael Salerno^1,2,3

¹Medicine, University of Virginia, Charlottesville, VA, United States, ²Radiology, University of Virginia, Charlottesville, VA, United States, ³Biomedical Engineering, University of Virginia, Charlottesville, VA, United States

First-pass contrast-enhanced myocardial perfusion imaging is a useful noninvasive tool to evaluate patients with coronary artery disease, but current techniques are still limited in spatial-temporal resolution, ventricular coverage and absolute quantification which reduces the sensitivity to detect perfusion differences between the endocardium and epicardium and quantify ischemic burden. In this study, we designed a dual-density dual-contrast spiral pulse sequence to achieve quantitative ultra-high resolution first-pass spiral perfusion imaging with whole heart coverage at 3T and further tested in 9 patients with suspected CAD undergoing cardiac catheterization.

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