Pixel-wise quantification of myocardial perfusion by dynamic contrast-enhanced magnetic resonance imaging allows for a non-invasive, observer independent and reproducible evaluation of the perfusion with high spatial resolution. The method suggested here, exploits the spatial smoothness of the perfusion using a spatial Tikhonov regularization to cope with the low signal-to-noise ratio of the data. This allows us to obtain quantitative perfusion values with high spatial resolution to detect small ischemic regions. The parameter regulating the strength of regularization is determined from the L-curve criterion and does not require any manual adjustments. The feasibility of the method is demonstrated in three patients.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords