Hybrid PET-MR imaging allows simultaneous measurement of myocardial blood flow (MBF) under identical physiological conditions. We sought to determine feasibility of simultaneous 13N-Ammonia PET and dynamic contrast-enhanced cardiovascular magnetic resonance (CMR) in healthy volunteers. 13N-Ammonia and gadolinium contrast were administered simultaneously during adenosine stress. Mean global stress MBF values for PET and CMR were 2.58 ± 0.11ml/g/min and 2.60 ± 0.47ml/g/min respectively. On a per territory basis, there was a moderate correlation (r = 0.63, p=0.03) and CMR underestimated PET MBF by 0.34ml/g/min (95% limits of agreement -0.49 to +1.18). Future studies in patients with CAD is warranted.
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